If Screw Attack or Plasma are available (or Gravity and a blue suit), farm the two Evirs closest to the door. With Wave or Spazer, it won't be possible to kill the second Evir in time, in which case the room can be crossed to reach a third one.

Requires:

{
  "resetRoom": {
    "nodes": [
      1
    ]
  }
}
"canPlayInSand"
"canDodgeWhileShooting"
{
  "or": [
    {
      "and": [
        "Gravity",
        "ScrewAttack",
        {
          "cycleFrames": 320
        }
      ]
    },
    {
      "and": [
        "Gravity",
        {
          "haveBlueSuit": {}
        },
        {
          "notable": "Blue Suit Sand Walk"
        },
        {
          "cycleFrames": 290
        }
      ]
    },
    {
      "and": [
        "Plasma",
        {
          "cycleFrames": 330
        },
        {
          "or": [
            "Gravity",
            {
              "and": [
                "canSuitlessMaridia",
                "HiJump",
                {
                  "cycleFrames": 50
                }
              ]
            },
            {
              "and": [
                {
                  "haveBlueSuit": {}
                },
                {
                  "notable": "Blue Suit Sand Walk"
                },
                {
                  "cycleFrames": 270
                }
              ]
            }
          ]
        }
      ]
    },
    {
      "and": [
        {
          "or": [
            "Wave",
            "Spazer"
          ]
        },
        "canFarmWhileShooting",
        {
          "cycleFrames": 975
        },
        {
          "or": [
            "Gravity",
            {
              "and": [
                "canSuitlessMaridia",
                "HiJump",
                {
                  "cycleFrames": 90
                }
              ]
            }
          ]
        }
      ]
    }
  ]
}

Resets obstacles: A

Farm cycle drops: 2 Evir

Dev note: Farming a third Evir is possible but would rarely be worthwhile.